CLINICAL SUMMARY

Green tea, coffee are linked to reduced mortality after stroke or MI

Teramoto M & al.. Stroke, 04 February 2021

Emily Willingham, PhD   |   11 February 2021

Takeaway

• Green tea intake is linked to reduced all-cause mortality following stroke or myocardial infarction (MI), and coffee intake is linked to mortality reduction after MI.
• Coffee intake is also associated with reduced all-cause mortality without a history of stroke or MI.

Why this matters

• Results from previous studies have been mixed.
• The question is of interest because of an aging population, improved acute survival after MI and stroke, and relevant lifestyle factors.

Key results

• 9253 deaths in median 18.5 years of follow-up.
• Adjusted risks (aHRs, 95% CIs) for poststroke mortality with green tea intake (vs none):
  • 1-6 cups/week: 0.73 (0.42-1.27).
  • 1-2 cups/day: 0.65 (0.36-1.15).
  • 3-4 cups/day: 0.56 (0.34-0.92).
  • 5-6 cups/day: 0.52 (0.31-0.86).
  • 7+ cups/day: 0.38 (0.20-0.71).
    • P trend=.002.
• Similar pattern post-MI.
• No association without stroke/MI history.
• Adjusted risks (aHRs, 95% CIs) for mortality without stroke/MI history, by coffee intake (vs none):
  • 1-6 cups/week: 0.86 (0.82-0.91).
  • 1 cup/day: 0.86 (0.80-0.92).
  • 2+ cups/day: 0.82 (0.77-0.89).
    • P trend<.001.
• Coffee was also linked to reduced mortality risk after MI:
  • 1-6 cups/week: 0.69 (0.53-0.91).
  • 1 cup/day: 0.78 (0.55-1.10).
  • 2+ cups/day: 0.61 (0.41-0.90).
• No association was seen between coffee intake and poststroke survival.
• Most deaths were cardiovascular.

Study design

• Prospective, questionnaire-based cohort study, Japan, with 46,213 participants (478 poststroke, 1214 post-MI), ages 40-79 years.
• Funding: Government grants.

Limitations

• Self-reported data.
• No tracking of behavioral changes.

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References  Disclaimer 

Teramoto M, Muraki I, Yamagishi K, Tamakoshi A, Iso H. Green Tea and Coffee Consumption and All-Cause Mortality Among Persons With and Without Stroke or Myocardial Infarction. Stroke. 2021 Feb 4 [Epub ahead of print]. doi: 10.1161/STROKEAHA.120.032273. PMID: 33535784

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