Δευτέρα 11 Μαΐου 2020

Very severe aortic stenosis

Posted by Mantzalardas Evanghelos | 12:35 μ.μ. |


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Very severe aortic stenosis: choosing the right time to perform valve replacement

  • Δευτέρα 11 Μαΐου 2020
  • Δύσκολο
In patients with very severe aortic stenosis (AS), early traditional valve replacement (VR) surgery (while asymptomatic) may be associated, compared to VR performed at a chosen time following a conservative approach (onset of symptoms), with rates of operative mortality and death during follow-up (composite endpoint) which are:
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A Korean randomised trial included 145 patients of this type (valve area ≤0.75 cm2; peak aortic jet velocity ≥4.5 m/sec or mean pressure gradient ≥50 mmHg) and showed that deaths were very significantly less frequent in the group who underwent early VR (1% vs. 15%). Deaths from any cause during the follow-up period were also less frequent in this group (7% vs. 21%).
Source: Early Surgery or Conservative Care for Asymptomatic Aortic Stenosis


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