Antibiotics and increased CVD risk

Antibiotics and increased CVD risk

Data from the Nurses' Health Study found one which of the following is associated with an increased risk for future cardiovascular disease in women?

• A

  A. ≥2 months of antibiotic use between ages 20 and 39 years
• B

  B. ≥2 months of antibiotic use between ages 40 and 59 years
• C

  C. ≥2 months of antibiotic use between age 60 years and older
• D

  *B and C
• E

  All of the above

• 
  ΠερισσότεραB
• C
• D
• E

Απαντήσεις συμπαικτών

Women who used antibiotics for 2 or more months at age 40 years or older had increased risk for cardiovascular disease in later life, with the risk highest for those who took long-term antibiotics after age 60 years. This may be connected to the effects of antibiotics on inflammation, the microbiome, and atherosclerosis development. Antibiotics can also result in prolongation of the QT interval, Torsades de Pointes, and even sudden cardiac death.

Reference

Heianza Y, Zheng Y, Ma W, Rimm EB, Albert CM, Hu FB, Rexrode KM, Manson JE, Qi L. Duration and life-stage of antibiotic use and risk of cardiovascular events in women. Eur. Heart J.2019;40(47):3838-3845. doi: 10.1093/eurheartj/ehz231. PMID: 31216010

Categories: